How to Choose the Best Digestive Enzymes

how to choose the best digestive enzymes

There are seemingly endless options on the market for digestive enzymes.

How do you know which one is right for you?

In this comprehensive guide, I will break down everything you need to know about digestive enzymes and how to choose the best one for your needs. I’ll discuss what they are, how they work, and the different types available.

By the end of this article, you’ll be an expert on digestive enzymes and will be able to choose the perfect one for your body.

Digestive Process

The digestive process is essential for breaking down our food and extracting our bodies’ nutrients. The process begins in the mouth, where chewing breaks down food into smaller pieces. From there, it travels down the esophagus and into the stomach. In the stomach, enzymes and acids further break down food. Finally, it enters the small intestine, where most absorption of nutrients takes place. Before defecation, the large intestine absorbs any remaining water, electrolytes, and vitamins, eliminating waste.

While this may seem like a simple process, many different things are happening along the way. Enzymes play a vital role in each digestion step, from breaking down complex carbohydrates to synthesizing essential vitamins and minerals.

digestive process

Various people may need different digestive enzyme supplements depending on their individual needs. For example, someone with celiac disease may need a supplement that contains gluten-specific proteases to digest gluten proteins properly. Those with lactose intolerance may benefit from taking a lactase supplement containing the enzyme lactase that breaks down lactose. And someone with a history of gastrointestinal issues may want to take a broad-spectrum digestive enzyme supplement that includes a variety of enzymes to support optimal digestion.

The best way to determine which digestive enzyme supplement is right for you is to talk to your doctor or a registered dietitian. They can help you understand your specific needs and find the best product for you. When choosing a product, be sure to read the label carefully. Some products may only contain one type of enzyme, while others may include multiple types. Ensure the product you choose has the enzymes you need to digest your food properly.

What are Digestive Enzymes?

Digestive enzymes help break down food into smaller particles that the body can absorb. They are produced naturally in the body but can also supplement form.

digestive enzymes for gut health

Digestive enzymes play a vital role in overall health, as they help the body extract nutrients from food and eliminate waste products.

How do Digestive Enzymes Work?

Digestive enzymes work by binding to food molecules and breaking them into smaller pieces. This process is known as hydrolysis.

Proteases break down protein molecules into amino acids, lipases break down fat molecules into fatty acids, and amylases break down carbohydrates into simple sugars.

Once the food is in smaller particles, it can be absorbed by the body and used for energy.

Benefits of Digestive Enzymes

There are many benefits of digestive enzymes:

  1. Improved digestion: Digestive enzymes help the body break down food more efficiently, resulting in better digestion and nutrient absorption.
  2. Increased nutrient absorption: By breaking down food into smaller particles, digestive enzymes help the body absorb more nutrients from food. Insufficient nutrient absorption can lead to deficiencies and health problems.
  3. Reduced inflammation: Digestive enzymes can help to reduce inflammation in the gut. Inflammation is when the body’s immune system responds to an infection or injury, and this response can cause swelling, pain, and redness. Digestive enzymes help to reduce inflammation by breaking down the inflammatory molecules in food.
  4. Relieve gas, bloating, and indigestion symptoms: Gas, bloating, and indigestion are common digestive issues caused by food intolerances or irritable bowel syndrome (IBS). Digestive enzymes can help relieve these symptoms by breaking down the offending molecules in food.
  5. Play a role in detoxification and weight loss: Digestive enzymes help the body eliminate toxins and absorb nutrients more efficiently, leading to weight loss and improved overall health.

Factors to Consider When Choosing Digestive Enzymes

When choosing a digestive enzyme, it’s essential to consider your individual needs and health goals. Here are some factors to keep in mind:

  • Your diet: If you eat many processed foods or have difficulty digesting certain nutrients, you may benefit from a digestive enzyme supplement.
  • Your health goals: If you’re looking to improve digestion or increase nutrient absorption, there are specific enzymes that can help you achieve these goals.
  • Any allergies or sensitivities: Be sure to check the ingredients list of any potential digestive enzyme supplements to ensure that you’re not allergic or sensitive to any of the ingredients.

What to Look for In Digestive Enzymes

When choosing a digestive enzyme supplement, there are several things to look for:

  • A high-quality product backed by science: Look for a product made from high-quality ingredients that have been third-party tested for purity and potency.
  • Broad Spectrum enzymes: A broad-spectrum enzyme supplement will contain a variety of enzymes that can help with different types of digestion.
  • Customizable dosage: Some supplements allow you to customize the dosage to meet your individual needs; this is helpful if you have sensitivities or allergies to certain ingredients.
  • A money-back guarantee: A good quality product will offer a money-back guarantee if you’re not satisfied with the results.
  • The suitable enzymes for your needs: Be sure to choose a product that contains the specific enzymes you need to achieve your health goals.
  • An affordable price: Digestive enzyme supplements can vary widely in price. Be sure to shop around and find a product that fits your budget.

Types of Digestive Enzymes

digestive enzymes pepslin bromelianThere are various types of digestive enzymes:

Protein Digestion

Proteases are enzymes that break down proteins into smaller peptides and amino acids.

  • Protease SP: Protease SP is a protease enzyme derived from Aspergillus oryzae. Protease treats digestive disorders such as indigestion, bloating, and gas.
  • Bromelain: Bromelain is a protease enzyme derived from pineapple. It has anti-inflammatory properties and can treat digestive issues such as IBS, Crohn’s disease, and ulcerative colitis.
  • Pepsin: Pepsin is a protease enzyme produced in the stomach. It helps to break down proteins into smaller peptides.

Carbohydrate Digestion

Carbohydrases are enzymes that break down carbohydrates into simple sugars.

  • Amylase: Amylase is an enzyme that breaks down starch into maltose and glucose. Amylase production happens in the pancreas and salivary glands.
  • Lactase: Lactase is an enzyme that breaks down lactose into glucose and galactose. Production happens in the small intestine.
  • Maltase: Maltase is an enzyme that breaks down maltose into glucose.

Fat Digestion

Lipases are enzymes that break down fats into glycerol and fatty acids.

  • Pancreatic lipase: Pancreatic lipase is an enzyme that breaks down triglycerides into free fatty acids and monoglycerides. Production happens in the pancreas.
  • Phospholipase A: Phospholipase A is an enzyme that breaks down phospholipids into free fatty acids and phospholipids. Its production is in the liver.

Nucleic Acid Digestion

Nucleases are enzymes that break down nucleic acids into nucleotides.

  • DNase: DNase is an enzyme that breaks down DNA into smaller fragments. Its production happens in the pancreas.
  • RNase: RNase is an enzyme that breaks down RNA into smaller fragments. Its produced in the liver.

Fruit Digestion

Fruits contain a type of carbohydrate called fructose. Fructolytic enzymes are needed to break down fructose into glucose.

  • Invertase: Invertase is an enzyme that breaks down sucrose into fructose and glucose, and its production is in the small intestines
  • Alpha-amylase: Alpha-amylase is an enzyme that breaks down starch into maltose, dextrin, and glucose. Production is in the pancreas and salivary glands.

How Long Do Enzymes Take to Work?

Enzymes begin working within minutes of taking them. However, it may take a few days or weeks to notice the full effect of the enzymes. If you don’t see any improvement after a few weeks, you may want to try a different product or dosage.

What to Expect After Taking Digestive Enzymes

After taking digestive enzymes, you may notice a decrease in gas, bloating, and indigestion. You may also see an increase in energy and overall well-being. If you have any adverse effects after taking enzymes, be sure to stop taking them and consult your healthcare provider.

How to Store Digestive Enzymes

The digestive enzyme storage is in a cool, dry place. Enzymes’ exposure to heat or moisture may cause them to lose their potency. Be sure to check the expiration date on the bottle and discard any expired enzymes.

Do Digestive Enzymes Have Any Side Effects?

Digestive enzymes are safe and well-tolerated. The most common side effect is bloating or gas. If you experience severe side effects, stop taking the enzymes and consult your doctor.


Digestive enzymes can be a helpful addition to your diet if you suffer from digestive issues. Be sure to choose a high-quality product that contains the specific enzymes you need. Always start with the lowest recommended dosage and increase as needed. If you experience any adverse effects, discontinue use and consult your healthcare provider.

When choosing a digestive enzyme supplement, it’s important to consider your individual needs and health goals. There are many different types of digestive enzymes available on the market, so be sure to do your research before purchasing. A qualified healthcare professional can also help you choose the best digestive enzyme for your needs.